Ageing
Tentative program
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Moderators:
Anna Sandgren, Linnaeus University
Nobuhiro Takahashi, Tohoku University
Yoshihisa Hirakawa, Nagoya University
Keynote Lectures
9:00-9:45 (SE)
16:00-16:45 (JP)
Ageing within the age of a pandemic
Boo Johansson, The University of Gothenburg
The pandemic demonstrates the need for a multidisciplinary perspective of ageing
Ingmar Skoog, The Univesity of Gothenburg
The societal response to Covid-19 and its effect on older adults wellbeing and everyday life
Q&A
Short Presentations
9:45-12:00 (SE)
16:45-19:00 (JP)
5-minute presentations by researchers from MIRAI 2.0 universities Sub-topics: Biological aspects of ageing; Psychosocial and Social aspects of ageing; Technological aspects of ageing.
Michael Annear, Waseda University
Active aging and the Olympic Games in 2021: A public health legacy lost?
Nina Karalija, Umeå University
Dopamine loss in the aging brain: insights from the Cognition, Brain, and Aging (COBRA) study
Swagata Das, Hiroshima University
Wearable soft robotics to perform at-home therapy and receive assistance in combating Osteoarthritis
Mattias Hedlund, Umeå University
High Intensity Training in aging: a HIT?
15 minute Q&A
15 MIN BREAK
Cong Wang, University of Tokyo
Poverty and Aging in Nepal
Cristina Joy Torgé, Jönköping University
Maintaining friendships: Older people’s social life during the covid-19 pandemic
Sai Sun, Tohoku University
Natural human tempo and its neural correlates
Therese Rydberg Sterner, The University of Gothenburg
COVID-19 among Swedish older adults– prevalence and feelings of worry in the H70-study
15 min Q&A
Joji Kusuyama, Tohoku University
Beneficial Effects of Exercise in the Middle Age on Metabolic Health Outcomes in Aging
Arianna Poli, Linköping University
Involvement of Older People in Research on Digital Health Technologies – Who Are We Missing
Parvaneh Emami, Hiroshima University
Effects of the compound in Broccoli on fission yeast cell viability
Sofia Andersson, Linnaeus University
Can Serious Illness Conversations be a way to increase quality of life for patients and their families?
KM Saif-Ur-Rahma, Nagoya University
Role of artificial intelligence in elder care
Anna Siverskog, Jönköping University
Shifting conditions for older people’s everyday life during a pandemic: A study on experiences of everyday experiences during the outbreak of Covid-19
15 min Q&A

Moderators:
Elenor Kristoffersson, Örebro university
Sofi Fristedt, Jönköping University
Yuto Kitamura, University of Tokyo
Kazuhiro Tsuga, Hiroshima University
Keynote Lectures
9:00-9:45 (SE)
16:00-16:45 (JP)
Ageing within the age of a pandemic
Hiroki Ohge, Hiroshima University Hospital
Effectiveness of 222-nm ultraviolet light on disinfecting microorganisms
Hozumi Motohashi, Tohoku University
Cytoprotective and Anti-Aging Function of NRF2 and its Role in Sulfur Metabolism
Q&A
Short Presentations
9:45-12:00 (SE)
16.45-19:00 (JP)
5-minute presentations by researchers from MIRAI 2.0 Universities
Sub-topics: Biological aspects of ageing; Psychosocial and Social aspects of ageing; Technological aspects of ageing.
Chisato Fujisawa, Nagoya University
Electrolyte Imbalance among the Older Adults
Andreea Badache, Örebro University
Living longer. Living well?
Minjung Lee, Waseda University
miRNAs are involved in accelerating aging
Daniel Globish, Uppsala University
Biomarker discovery for pancreatic cancer to promote health and wellbeing of the elderly population
15 min Q&A
15 MIN BREAK
Taro Kusama, Tohoku University
Oral health and mental health in older adults: The social aspects of oral function
Carmen Solares Canal, Örebro University
Older offenders: Understanding the relation between criminal behaviour, health disorders and psychosocial status in ageing
Md Razib Mamun, Nagoya University
Multi-professional collaboration in dementia care
Pär Bjälkebring, University of Gothenburg
Older adults reactions and decisions for own, others, and societal well-being in time of a pandemic
15 min Q&A
Ruriko Otomo, Hokkaido University
Language and migration in the age of graying society
Sarfraz Iqbal, Linnaeus University
Exploring the Use and impact of medication management robots in home healthcare
Yukiko Hirano, Nagoya University
Current situation surrounding “aging” in Japan
Erik Smedberg, Lund University
Safe building evacuation for all
Pattaphol Yuktadatta, Hiroshima University
Exercise Behaviour in Japan and the United States
15 min Q&A

Workshop
9:00-12:00 (SE)
16:00-19:00 (JP)
How to plan your research impact with UCD impact planning canvas
Impact Planning Canvas is a tool for identifying the possible impact and planning for how you can achieve it in the best way. Based on research results and on the researcher’s terms. After an introduction of the concept as well as being introduced to the tool you will have the possibility to use your own research as a base for the exercise. The session will be held in break-out room where practical help and guidance from an experienced innovation advisor will be given for individual support.
Facilitator: Urban Bergquist, Linnaeus University
Academia/Industry Matchmaking Event
9:00-12:00 (SE)
16:00-19:00 (JP)
Artificial intelligence and the future of healthcare for older populations
The MIRAI2.0 Innovation and Entrepreneurship Advisory Group (IEAG) organises a matchmaking event that will offer a great opportunity for academics, researchers, and industrial players from both countries to network, present research progress and address new challenges, while identifying potential ideas for future collaboration and seed projects.
Following the event, VINNOVA, the Swedish government innovation agency, will launch a call for proposals to award funding to new collaborations between Sweden and Japan in AI, Ageing, Sustainability, Material Science and Innovation/Entrepreneurship.

Moderators:
Carl-Johan Boraxbekk, Umeå University
Takayuki Akimoto, Waseda University
Short Presentations
9:00-10:30 (SE)
16:00-17:30 (JP)
5-minute presentations by researchers from MIRAI 2.0 Universities
Sub-topics: Biological aspects of ageing; Psychosocial and Social aspects of ageing; Technological aspects of ageing.
Yohei Jinno, Kyushu University
What is the key factor for early failure of dental implants?-Saliva contamination during surgery?
Petra Sandberg, Umeå University
Ancient mnemonic in new format: promoting cognitive health in old age by app-based learning
Hinako Ito, Waseda University
Association between Loneliness and Living Activities among Living-Alone Senior
Sofi Fristedt, Jönköping University
Digital exclusion and inclusion in later life – in the light of the pandemic and beyond
15 min Q&A
Rahmatika Dewi, Hiroshima University
From digital skill divide to digital-human skill nexus for job sustainability
Sofia Backåberg, Linnaeus University
Confidence in every step – using interactive technology to enhance functional mobility and balance in daily living among older adults
Yizhou Yang, Waseda University
Experimental and Numerical study on the effect of corrosion on bond behavior of RC structure and its Rehabilitation
Sai Krishna, Örebro University
Robotics for successful Ageing
15 min Q&A
Summary
Closing Ceremony
10:45-12:00 (SE)
16:00-17:30 (JP)
Reporting from parallel scientific sessions (all topics)
Information about funding opportunities
Closing Remarks
SPEAKERS

Boo Johansson
PhD, Senior Professor of Geropsychology,
University of Gothenburg
Boo Johansson is a senior professor at the Department of Psychology at the University of Gothenburg. He specializes in geropsychology. Prof Johansson’s research interests include cognition, cognitive and mental health in late adulthood and aging. Normal aging, compromised cognition, and dementia. Clinical, twin, and longitudinal population-based aging studies. He is a steering committee member of AgeCap Centre for Ageing and Health, a multidisciplinary research centre hosting more than 160 researchers from 25 disciplines working interdisciplinary to increase the quality of life and societal participation of older persons.
The pandemic demonstrates the need for a multidisciplinary perspective of ageing
Research on ageing requires broad multidisciplinary perspectives. At the fundamental level, the focus is on age-related underlying biological changes in cells, tissues and organ systems which affects functioning and ultimately survival. At focus at the psychological level are mental and neural processes involved in cognition, experiences of wellbeing and how this is reflected in individuals coping behavior with internal and external environmental demands. Social ageing refers to how individuals are viewed and treated depending on their age and how this affects older adults’ integration and participation in the societal life. The current Covid-19 pandemic clearly illustrates the need to take all the above perspectives into account for determination of age-related risks from a biological, psychological, and social perspective, and how this knowledge can inform societal policies, preventative, and treatment interventions.

Ingmar Skoog
MD., Ph.D, Professor of Psychiatric epidemiology,
University of Gothenburg
Ingmar Skoog is the Director of the Centre for Ageing and Health AGECAP, including 130 researchers from 16 institutions and 6 faculties at the University of Gothenburg, Sweden, and is leading the Neuropsychiatric Epidemiology Unit (Epinep) at the Sahlgrenska Academy. He has been involved in epidemiological research since 1983, and is PI of the Gothenburg H70 Birth Cohort Studies, including the 95+ study. He has published more than 400 scientific papers, and been invited speaker to more than 300 international meetings. His main research interest is the epidemiology of ageing, including time-trends, and dementia, and mental disorders in old age. (M.D. in 1985, Ph.D. in 1993, specialist in psychiatry 1993, and professor in Psychiatry in 2001)
The societal response to Covid-19 and its effect on older adults wellbeing and everyday life
In Sweden, it soon became clear that authorities and experts in virology lacked knowledge about aging. Much emphasize during the first wave of the pandemic was put on protecting and isolating people above age 70 years, who were all regarded to be frail and helpless. This led to a lot of ageism and prejudice about older people in a country where the view of older people was already negative. However, it soon became clear that 75% of all deaths in covid 19 occurred among the 3% of the population who had old age care. This took authorities by some surprise. Reasons included that people in old age care are frail, but also that they meet more younger people at a very close distance than any other group in society. This led to a lot of discussion in Sweden about different aspects of old age care, and the quality of the care.

Hiroki Ohge
M.D., Professor, Department of Infectious Diseases, Hiroshima University Hospital
Effectiveness of 222-nm ultraviolet light on disinfecting microorganisms
Approximately half of the surfaces present in hospital premises are insufficiently cleaned during the manual cleaning. Recently, non-touch disinfection technologies using ultraviolet (UV) light have been increasingly used in health care settings in an attempt to decrease the transmission of nosocomial pathogens and prevent health care-associated infections.Most UV disinfection systems use germicidal lamps emitting UV radiation C (UVC) around 254 nm. However, it is well known that 254-nm UVC is harmful to the skin and eyes. Previous reports demonstrated that 222-nm UVC light, belonging to far-UVC (207-222 nm), has the same highly effective germicidal proper-ties as 254-nm UVC; however, it is less harmful to the skin and eyes than 254-nm UVC because far-UVC light has a very limited penetration depth in the skin or eye. Our group demonstrated the efficacy of 222-nm UVC irradiation against SARS-CoV-2 or multidrug-resistant bacterial contamination in in vitro experiment. Further evaluations of the safety of 222-nm UVC light to the skin and eyes are required to establish an effective strategy for UV disinfection of hospital or public space.

Hozumi Motohashi
M.D., Professor at Institute of Development, Aging and Cancer, Tohoku University
Cytoprotective and Anti-Aging Function of NRF2 and its Role in Sulfur Metabolism
Keap1-NRF2 system is a sulfur-based cytoprotection mechanism and makes critical contributions to prevention and alleviation of various diseases relating to oxidative stress. Recent studies of ours and others also clarified that appropriate activation of NRF2 has anti-aging effects by limiting accumulation of oxidative damages of tissues.
KEAP1 utilizes multiple cysteine residues for sensing electrophiles, whereas NRF2 activates various genes regulating sulfur-involving reactions. Although NRF2 enhances mitochondrial activity, a precise mechanism has not been fully understood. Based on our recent finding that mitochondrial sulfur metabolism makes a substantial contribution to mitochondrial energy metabolism, we hypothesized that NRF2 promotes the mitochondrial activity through promoting the sulfur metabolism. Since SLC7A11 encoding a cystine transporter, xCT, is a well-known NRF2 target gene, NRF2 was likely to enhance the mitochondrial sulfur metabolism by increasing the supply of their substrate, cysteine.
Indeed, cystine restriction in the culture medium and xCT inhibition by sulfasalazine both decreased the mitochondrial membrane potential (MMP), suggesting that sufficient cysteine availability is required for the maintenance of MMP.
To examine contributions of the mitochondrial sulfur oxidation pathway mediated by SQOR, ETHE1 and SUOX and the mitochondrial persulfide production catalyzed by CARS2 to the MMP maintenance, we knocked down each enzyme gene and examined its impact on the MMP. The MMP was significantly decreased by knockdown of these enzymes except for SUOX. Among them, we found that SQOR, encoding sulfide-quinone oxidoreductase (SQOR), is directly activated by NRF2. Increased mitochondrial membrane potential by NRF2 activation was canceled by simultaneous suppression of SQOR. These results suggest that one of the mechanisms for NRF2-dependent mitochondrial activation is the facilitation of sulfur metabolism in mitochondria following the increased cystine uptake.

Michael Annear
Associate professor
Faculty of Sport Sciences, Waseda University

Nina Karalija
Senior research engineer
Department of Radiation Sciences,
Umeå University

Swagata Das
Specially appointed Assistant Professor
Electrical, Systems, and Control Engineering, Hiroshima University

Mattias Hedlund
Associate professor,
Department of Community Medicine and Rehabilitation, Umeå University

Cong Wang
Student
University of Tokyo

Cristina Joy Torgé
Ph.D.
Ageing and Later Life
Institute of Gerontology, Jönköping University

Sai Sun
Assistant professor
Frontier Research Institute for Interdisciplinary Sciences, Tohoku University

Therese Rydberg Sterner
Ph.D
The University of Gothenburg

Joji Kusuyama
Assistant Professor
Frontier Research Institute for Interdisciplinary Sciences, Tohoku University

Arianna Poli
Ph.D
Department of culture and society,
Linköping University

Parvaneh Emami
Student
Integrated sciences for life,
Hiroshima University

Sofia Andersson
Department of Health and Caring Sciences, Linnaeus University

KM Saif-Ur-Rahma
Ph.D fellow
Public Health and Health Systems,
Nagoya University

Anna Siverskog
Assistant professor and Ph.D scholar
Social Work, Jönköping University

Chisato Fujisawa
Physician
Geriatric and gerontology,
Nagoya University

Andreea Badache
Ph.D. candidate
Disability Sciences at School of Health Sciences, Örebro University

Minjung Lee
Assistant professor
Faculty of Sport Sciences, Waseda University

Daniel Globish
Senior lecturer/Associate professor
Department of Chemistry – BMC, Analytical Chemistry; Globisch group, Uppsala University

Taro Kusama
Assistant professor
Liaison Center for Innovative Dentistry,
Tohoku University

Carmen Solares Canal
Ph.D
School of Law, Psychology and Social Work,
Örebro University

Md Razib Mamun
Ph.D
Public Health and Health Systems,
Nagoya University

Pär Bjälkebring
Ph.D. in Psychology,
Department of Psychology,
University of Gothenburg

Ruriko Otomo
Associate Professor
Research Faculty of Media and Communication, Hokkaido University

Sarfraz Iqbal
Assistant professor
Department of Informatics,
Linnaeus University

Yukiko Hirano
Laboratory technician
International health and health systems,
Nagoya University

Erik Smedberg
Doctoral student
Division of Fire Safety Engineering,
Lund University

Pattaphol Yuktadatta
Doctoral student
Graduate School of Humanities and Social Science, Hiroshima University

Yohei Jinno
Assistant Professor
Faculty of Dentistry, Division of Oral Rehabilitation, Kyushu University

Petra Sandberg
Senior research engineer
Department of Radiation Sciences,
Umeå University

Hinako Ito
Master student
Creative Science and Engineering,
Waseda University

Sofi Fristedt
Associate Professor
Department of Rehabilitation, School of Health and Welfare, Jönköping University

Rahmatika Dewi
Doctoral student
Humanities and Social Sciences,
Hiroshima University

Sofia Backåberg
Senior lecturer
Department of Health and Caring Sciences, Linnaeus University

Yizhou Yang
Assistant Professor
Waseda Research Institute for Science and Engineering, Waseda University

Sai Krishna
Ph.D
School of Science and Technology,
Örebro University